Anticancer activity of fruit and leaf extracts of pandanus odoratissimus on human breast cancer (MCF-7) cell line
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Date
2014
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Universiti Malaysia Terengganu
Abstract
Natural products play an important role in production of new drugs, new drug leads
and new chemical entities. Pandanus odoratissimus (Pandanaceae) is one of the most
popular herbs and locally grows in Malaysia, and has been used traditionally to
Ayurvedic medicine cure certain diseases. The present study is aimed to find out
antioxidant and anticancer activity of P. odoratissimus against human breast cancer
cell lines (MCF-7). Antioxidant activity has been measured by using 2, 2-diphenyl-1-
picrylhydrazyl (DPPH) free radical scavenging activity and core showed highest
antioxidant value among the other extracts. The effects of plant's parts on MCF-7 cell
lines were determined using [3-( 4, 5-dimethylthiazolyl)-2, 5-diphenyl-tetrazolium
bromide], MTT assay.
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Rodhiyah Yahya, LP 38 PPSMS 1 2014