Fabrication and characterization of gellan gum films incorporating nanostructured titanium dioxide for wound dressing applications

dc.contributor.authorNur Arifah Binti Ismail
dc.date.accessioned2020-11-22T03:15:56Z
dc.date.available2020-11-22T03:15:56Z
dc.date.issued2019
dc.description.abstractTitanium dioxide (TiO2) nanostructures, which are nanoparticles, nanorods and nanotubes, were successfully synthesised by using the hydrothermal method. These TiO2 nanostructures were incorporated into gellan gum (GG) film. Good film was produced by using 1.00 g GG with a 5 mM CaCl2 cross-linker and 50% w/w glycerol as a plasticiser dried at 50 °C for 24 h. GG incorporating TiO2 nanoparticles (GG+TiO2-NPs), nanorods (GG+TiO2-NRs) and nanotubes (GG+TiO2-NTs) was produced via the evaporative casting method. GG+TiO2-NTs film shows the best mechanical properties, a high swelling ability and moderate water vapour transmission rates attributed to the chemical interaction between GG and TiO2 nanotubes. GG+TiO2-NTs film also shows antibacterial properties with 10 ± 0.38 mm, 12 ± 0.06 mm, 11 ± 0.06 mm and 10 ± 0.12 mm inhibition zone was obtained against Staphylococcus aureus, Streptococcus, Escherichia coli and Pseudomonas aeruginosa, which are as good as control samples (penicillin).en_US
dc.identifier.urihttps://umt-ir.umt.edu.my/xmlui/handle/123456789/14598
dc.language.isoenen_US
dc.publisherUniversiti Malaysia Terengganuen_US
dc.subjectTP 978 N82 2019en_US
dc.subjectGellan gumen_US
dc.subjectTitaniumen_US
dc.titleFabrication and characterization of gellan gum films incorporating nanostructured titanium dioxide for wound dressing applicationsen_US
dc.typeThesisen_US
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