Hibiscus tiliaceus as potential source for antioxidant and anticancer agent
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Date
2014
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Universiti Malaysia Terengganu
Abstract
Hibiscus tiliaceus (Sea hibiscus) is a tree that grows in the coastal environment and
widely distributed in tropical mangroves regions. The objectives of this study are to
know the antioxidant activity of the extracts of H. tiliaceus by using the 2,2-diphenyl
l-piicrylhydrazyl (DPPH) assay and to study the anticancer activity of H. tiliaceus
extracts against MCF-7 human breast cancer cells by using the MTT assay. Quercetin
was used as standard for antioxidant and anticancer activities. The extract used are
methanol, hexane, ethyl acetate and water extracts from the flower (HMF, HHF,
HEAF and HWF), seed (HMS, HHS, HEAS and HWS) and leaf (HML, HHL, HEAL
and HWL) of H. tiliaceus. In quantitative assay of antioxidant, ten of sample extracts
(HMF, HMS, HML, HHS, HEAF, HEAS, HEAL, HWF and HWL) contained
antioxidant activity higher than quercetin which has IC50 of 0.127 mg/ml and tw
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Noor Zulaikha Shamsudin, LP 29 PPSMS 1 2014