Synthesis, Spectroscopic Studies, and Biological Activities of Acylthiourea Derivatives as Potential Anti-Bacteria Agents

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dc.contributor.authorWan M. Khairul
dc.contributor.authorAziah Ahmad Ariffin
dc.contributor.authorNoraznawati Ismail
dc.contributor.authorAdibah Izzati Daud
dc.date.accessioned2017-04-11T00:19:29Z
dc.date.available2017-04-11T00:19:29Z
dc.date.issued2016
dc.description.abstractThiourea is known to be a unique class of organic compounds especially acylthiourea since they consist excellent Hbonds donor and acceptor where it has strong ability to form metal complexation with various metal salts. Therefore, six members of acylthiourea derivatives (TH1-TH6) have been successfully synthesized and characterised using selected spectroscopic and analytical methods namely Fourier-Transform Infrared (FT-IR) spectroscopy, UV-visible (UV-vis) spectrophotometer, and CHNS elemental analysis. In turn, all the synthesised TH1-TH6 were used to investigate the anti-bacterial activity towards selected bacteria of both Gram-negative and positive namely Salmonella typhi and Bacillus cereus respectively. TH1-TH6 revealed to have good activity towards S. typhi and B. cereus with specific and broad-range spectrum activity.en_US
dc.identifier.citationVol. 3 (1) ; 13-19 p.en_US
dc.identifier.urihttp://hdl.handle.net/123456789/5637
dc.language.isoenen_US
dc.publisherEducatum JSMTen_US
dc.subjectThioureaen_US
dc.subjectSpectroscopicen_US
dc.subjectAntibacterialen_US
dc.subjectSynthesisen_US
dc.subjectCharacterisationen_US
dc.titleSynthesis, Spectroscopic Studies, and Biological Activities of Acylthiourea Derivatives as Potential Anti-Bacteria Agentsen_US
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