Recent advances of nucleotide nutrition research in aquaculture: a review
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Date
2019-06
Journal Title
Journal ISSN
Volume Title
Publisher
Wiley Publishing Asia Pty Ltd
Abstract
Although nucleotides (NT) have long been implicated as feed attractants in both
vertebrate and invertebrate species, research into potential growth and health benefits
of dietary NT in aquaculture species has just been implemented in early
2000s. To date, research pertaining to NT supplementation in aquafeed as functional
nutrients has shown rather consistent and encouraging, beneficial results in
fish and shrimp health management. Dietary NT serve a marked role to enhance
growth in early stages of development, improve reproductive performances of
brood fish, enhance larval quality, increase stress and disease resistance, modulate
immune functions and improve intestinal morphology and gut microbiota of fish
and shrimp. NT have also been used as functional supplement in alternative protein
based diet, where NT was found as an effective supplement to increase the
efficiency of utilizing alternative proteins. However, still there are numerous gaps
in existing knowledge about exogenous NT administration to fish and shrimp
including various aspects of digestion, absorption, metabolism, administration
duration and age/size-related responses. Adoption of different molecular technologies,
like proteome modification and study of several gene expression pattern
related to growth, immunity, gut health and stress resistance in details are important
for exploring the underlying mechanisms of NT functions in improved
growth and health performances of fish and shrimp. Efforts are also needed on
production technologies to reduce the NT cost. Moreover, extensive research
information is also required regarding the use of NT in alternative protein and
lipid based diet to develop cost-effective, ecofriendly functional aquafeed in near
future.
Description
Keywords
aquaculture, fish performances, functional nutrient, immunonutrition, immunostimulant, nucleotide