Phenyl ethanone and sterols from Acanthaster planci as potential PPAR-ligand

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dc.contributor.authorNurul Hazirah Mat Lazim
dc.contributor.authorAsnuzilawati Asari
dc.contributor.authorFaridah Mohamad
dc.contributor.authorTg. Muhammad T. S.
dc.contributor.authorNoraznawati Ismail
dc.contributor.authorMariam Taib
dc.contributor.authorAziz Ahmad
dc.contributor.authorHabsah Mohamad
dc.date.accessioned2017-04-09T02:30:51Z
dc.date.available2017-04-09T02:30:51Z
dc.date.issued2015
dc.description.abstractA new phenyl ethanone (1-[4-(1,4-diamino-heptyl)-phenyl]-ethanone (1))and two known sterols (stigmasterol (2) and β–sitosterol (3))were succesfully isolated from methanolic extract of Acanthaster planci collected from the East Coast of Peninsular Malaysia. The chemical structures of compounds 1-3 were deduced on the basis of extensive spectral data (1D and 2D NMR), MS and IR spectroscopy techniques; as well as in comparison the data with those reported in the literature.Compounds 1-3were not toxic towards HepG2 cells and displayed as a potential peroxissome proliferator activated receptor (PPAR) ligand.en_US
dc.identifier.citationVol. 7 (9)en_US
dc.identifier.urihttp://hdl.handle.net/123456789/5323
dc.language.isoenen_US
dc.publisherJournal of Chemical and Pharmaceutical Researchen_US
dc.subjectAcanthaster plancien_US
dc.subjectPPARen_US
dc.subjectsterolsen_US
dc.subjectphenyl ethanoneen_US
dc.subjectluciferaseen_US
dc.titlePhenyl ethanone and sterols from Acanthaster planci as potential PPAR-liganden_US
dc.typeArticleen_US
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