Exploiting Fatty Acid-Polymer-Based Lauric Acid and Chitosan as Coating Material for Drug Encapsulation

dc.contributor.author	Sabiqah Tuan Anuar
dc.contributor.author	Patricia nellane Ithurayasamy
dc.contributor.author	Laili Che Rose
dc.date.accessioned	2017-04-11T03:31:30Z
dc.date.available	2017-04-11T03:31:30Z
dc.date.issued	2016
dc.description.abstract	A hybrid of saturated fatty acid and natural polymer was exploited as a coating material to encapsulated drug. Thus in this research, both lauric acid (C12 fatty acid) and chitosan were used as coating formulation for drug release at two different pH (1.2 and 6.8). The combination of fatty acid and chitosan, a linear polysaccharide, provides a better control of the drug release by selectively releasing the encapsulated drug in the selected pH. Results from FTIR and SEM showed that lauric acid-chitosan capsule coating is proven to have a film forming capability and stability with a controlled drug release at the mimicking human colon area pH. Moreover, initial study using in-vitro dissolution method indicated their capability to form a membrane and protect the drug from degradation.	en_US
dc.identifier.uri	http://hdl.handle.net/123456789/5682
dc.language.iso	en	en_US
dc.publisher	Middle-East Journal of Scientific Research	en_US
dc.subject	C12 fatty acid	en_US
dc.subject	Chitosan	en_US
dc.subject	Drug encapsulated	en_US
dc.subject	Cross-linking	en_US
dc.subject	in-vitro method	en_US
dc.subject	FTIR	en_US
dc.title	Exploiting Fatty Acid-Polymer-Based Lauric Acid and Chitosan as Coating Material for Drug Encapsulation	en_US
dc.type	Article	en_US

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