Browsing by Author "Sabiqah Tuan Anuar"

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    Exploiting Fatty Acid-Polymer-Based Lauric Acid and Chitosan as Coating Material for Drug Encapsulation
    (Middle-East Journal of Scientific Research, 2016) Sabiqah Tuan Anuar; Patricia nellane Ithurayasamy; Laili Che Rose
    A hybrid of saturated fatty acid and natural polymer was exploited as a coating material to encapsulated drug. Thus in this research, both lauric acid (C12 fatty acid) and chitosan were used as coating formulation for drug release at two different pH (1.2 and 6.8). The combination of fatty acid and chitosan, a linear polysaccharide, provides a better control of the drug release by selectively releasing the encapsulated drug in the selected pH. Results from FTIR and SEM showed that lauric acid-chitosan capsule coating is proven to have a film forming capability and stability with a controlled drug release at the mimicking human colon area pH. Moreover, initial study using in-vitro dissolution method indicated their capability to form a membrane and protect the drug from degradation.
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    Microplastics Ingestion by Scapharca cornea at Setiu Wetland, Terengganu, Malaysia
    (Middle-East Journal of Scientific Research, 2016) Yusof Shuaib Ibrahim; Alyza Azzura Azmi; Shaakirah Abdul Shukor; Sabiqah Tuan Anuar; Siti Aishah Abdullah
    Filter feeding bivalves are among the keystone species in marine environment that maintains or improves water quality and nutrients cycling between the water column and bottom dwelling organsims. Ingestion of microplastics by these organisms provides a possible step for the transfer of pollutants and plastics additives. Ingestion of microplastics in Scapharca cornea were determined and quantified at its natural habitat in Setiu Wetland, Terengganu, Malaysia. A total of 120 wild S. cornea bivalves were handpicked from three stations. Microplastics were extracted by alkali digestion (10 M of NaOH) and then identified visually according to their physical characteristics: shape, colour size and density. Most of the microplastics particles present were filaments. Fourier Transform Infrared Spectroscopy analysis of the microplastics showed the presence of strong peaks associated with polyethylene and polyamide.