Please use this identifier to cite or link to this item: http://umt-ir.umt.edu.my:8080/handle/123456789/8225
Full metadata record
DC FieldValueLanguage
dc.contributor.authorLeni Marlina-
dc.date.accessioned2018-02-01T00:37:18Z-
dc.date.available2018-02-01T00:37:18Z-
dc.date.issued2016-
dc.identifier.urihttp://hdl.handle.net/123456789/8225-
dc.description.abstractOver the past few decades, inflammation has been recognized as a major risk factor for various human diseases. They have three major group of drugs used in threaten of inflammatory diseases, such as corticosteroids, non steroidal anti-inflammatory drugs (NSAID) and disease modifying anti rheumatoid drugs (DMARDs). Unfortunately, these drugs may have too many side effects in the body. Therefore, an alternative drug from the nature especially from marine natural product was investigated in this study to confirm their potency as anti-inflammatory agent. Study on marine sponge Haliclona amboinensis-associated bacteria as anti-inflammatory potential agents was done by inhibiting of inducible nitric oxide synthase (iNOS), cyclooxygenase-1 (COX-1), cyclooxygenase-2 (COX-2), and phospholipase A2 (sPLA2) enzymes. Result revealed that all samples were inhibited COX-1, COX-2 and sPLA2 enzymes activities compare to arginine as a control.en_US
dc.language.isoenen_US
dc.publisherTerengganu: Universiti Malaysia Terengganuen_US
dc.subjectQL 373 .D4 L4 2016en_US
dc.subjectLeni Marlinaen_US
dc.subjectDemospongiaeen_US
dc.subjectAnti-inflammatory agentsen_US
dc.titleInvestigation on anti-inflammatory activities and mechanisms of action of bacteria associated with marine sponge haliclona amboinensisen_US
dc.typeThesisen_US
Appears in Collections:Institut Bioteknologi Marin

Files in This Item:
File Description SizeFormat 
QL 373 .D4 L4 2016 Abstract.pdf37.77 kBAdobe PDFView/Open
QL 373 .D4 L4 2016 Full Text.pdf
  Restricted Access
952.38 kBAdobe PDFView/Open Request a copy


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.