Morphological analysis on the toxic effect of manganese on Acanthamoeba sp. isolated from Setiu Wetland, Terengganu

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DC Field	Value	Language
dc.contributor.author	Fatimah Hashim	-
dc.contributor.author	Nur Athirah Abdul Rahman	-
dc.contributor.author	Nakisah Mat Amin	-
dc.date.accessioned	2017-04-16T08:37:06Z	-
dc.date.available	2017-04-16T08:37:06Z	-
dc.date.issued	2015	-
dc.identifier.uri	http://hdl.handle.net/123456789/5878	-
dc.description.abstract	Manganese (Mn) is one of the common pollutants found in aquatic environment that are difficult to destroy and very persistent in the water body. Excessive levels of Mn in the aquatic environment have threatened some of the aquatic organisms including free-living Acanthamoeba sp. In this study, Mn was assessed for its cytotoxicity and genotoxicity on Acanthamoeba sp. isolated from Setiu Wetland, Terengganu. IC50 value of Mn obtained was 24 ppm while morphological observation indicates that Acanthamoeba sp. underwent apoptotic and necrotic mode of cell death after exposure to Mn for 24 hours at 30°C. This metal is also able to induce mild genotoxicity towards the DNA of Acanthamoeba sp.	en_US
dc.language.iso	en	en_US
dc.publisher	Procedia Environmental Science	en_US
dc.subject	Cytotoxicity	en_US
dc.subject	genotoxicity	en_US
dc.subject	alkaline comet assay	en_US
dc.subject	heavy metal	en_US
dc.title	Morphological analysis on the toxic effect of manganese on Acanthamoeba sp. isolated from Setiu Wetland, Terengganu	en_US
dc.title.alternative	An in vitro study	en_US
dc.type	Article	en_US
Appears in Collections:	Journal Articles

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