Cultured marine bacteria isolated from sponges for discovery of bioactive compounds

Abstract

Association of marine bacteria and sponges was vastly reported since decades ago. Their contribution in the discovery of new bioactive compounds is also not a new issue. Interestingly, structural similarities between the metabolites of the sponge and its associated bacteria, those found within its tissue, indicate that these compounds are of bacterial origin. This study was conducted to isolate and characterize bacteria from marine sponges and to investigate the release of antibacterial compounds from marine isolates under ecologically relevant conditions.