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dc.contributor.authorSiti Nor Khadijah Addis-
dc.date.accessioned2012-07-24T03:18:23Z-
dc.date.available2012-07-24T03:18:23Z-
dc.date.issued2011-11-
dc.identifier.urihttp://hdl.handle.net/123456789/1653-
dc.description.abstractFlaviviruses are a group of positive-strand RNA viruses of global significance. The flavivirus RNA genome encodes a single open reading frame that is directly translated into a single polyprotein and cleaved by host and virally encoded proteases prior to protein maturation. Hence, the proteolytic cleavage events play a central role in the process of viral gene expression in flaviviruses. Despite the importance of these events, the mechanism of proteolytic cleavage leading to the generation of the two non-structural proteins, NS1 and NS2A is poorly defined.en_US
dc.language.isoenen_US
dc.publisherAustralian national Universityen_US
dc.relation.ispartofseries;QP 609 .P78 S5 2011-
dc.subjectQP 609 .P78 S5 2011en_US
dc.subjectSiti Nor Khadijah Addisen_US
dc.subjectTesis The Australian National University 2011en_US
dc.subjectProteolytic enzymesen_US
dc.titleGenetic and functional analysis of the proteolytic cleavage at the junction of the NS1 and NS2a proteins of murray valley encephalitis virusen_US
dc.typeThesisen_US
Appears in Collections:Staff Thesis

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