Please use this identifier to cite or link to this item: http://umt-ir.umt.edu.my:8080/handle/123456789/5323
Title: Phenyl ethanone and sterols from Acanthaster planci as potential PPAR-ligand
Authors: Nurul Hazirah Mat Lazim
Asnuzilawati Asari
Faridah Mohamad
Tg. Muhammad T. S.
Noraznawati Ismail
Mariam Taib
Aziz Ahmad
Habsah Mohamad
Keywords: Acanthaster planci
PPAR
sterols
phenyl ethanone
luciferase
Issue Date: 2015
Publisher: Journal of Chemical and Pharmaceutical Research
Citation: Vol. 7 (9)
Abstract: A new phenyl ethanone (1-[4-(1,4-diamino-heptyl)-phenyl]-ethanone (1))and two known sterols (stigmasterol (2) and β–sitosterol (3))were succesfully isolated from methanolic extract of Acanthaster planci collected from the East Coast of Peninsular Malaysia. The chemical structures of compounds 1-3 were deduced on the basis of extensive spectral data (1D and 2D NMR), MS and IR spectroscopy techniques; as well as in comparison the data with those reported in the literature.Compounds 1-3were not toxic towards HepG2 cells and displayed as a potential peroxissome proliferator activated receptor (PPAR) ligand.
URI: http://hdl.handle.net/123456789/5323
Appears in Collections:Journal Articles

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