http://umt-ir.umt.edu.my:8080/handle/123456789/3189 2026-08-17T06:16:12Z http://umt-ir.umt.edu.my:8080/handle/123456789/23415 Title: BIOEFFICACY OF ENTOMOPATHOGENIC FUNGUS (Metarhizium anisopliae) STRAIN MET-GRA4 AGAINST GOLDEN APPLE SNAIL (Pomacea canaliculata) Authors: MOHAMAD IKMAL HAKIM BIN ALLAHUDIN 2025-07-01T00:00:00Z http://umt-ir.umt.edu.my:8080/handle/123456789/23412 Title: FORMULATION AND OPTIMIZATION VIA RESPONSE SURFACE METHODOLOGY AND GREENNESS EVALUATION OF CREATINE-FUNCTIONALIZED MAGNETIC ADSORBENTS AS A MICRO-SCALE EXTRACTION TOOL FOR ANTIDEPRESSANT DRUG ANALYSIS Authors: KHIRTANA RAVEENDRAN Abstract: , 2025-12-01T00:00:00Z http://umt-ir.umt.edu.my:8080/handle/123456789/21135 Title: ELUCIDATION OF POTENTIAL PROTEINS ASSOCIATED WITH Vibrio parahaemolyticus INFECTION IN WHITELEG SHRIMP, Penaeus vannamei USING HOST-PATHOGEN PROTEIN-PROTEIN INTERACTION NETWORK ANALYSIS Authors: NUR FATHIAH ROSILAN 2024-01-01T00:00:00Z http://umt-ir.umt.edu.my:8080/handle/123456789/16423 Title: SYNTHESIS, CHARACTERISATION, CYTOTOXIC ACTIVITY EVALUATION AND STRUCTURE-ACTIVIITY RELATIONSHIP STUDY OF NEW FERROCENE-INDOLE DERIVATIVES AS POTENTIAL ANTICANCER AGENTS Authors: LIEW KEN MIN Abstract: Ferrocene-indole is a series of organometallic molecules that consist of a ferrocene moiety directly or indirectly attached to an indole core at any possible position of substitution. A series of seven new ferrocene-indole molecules was synthesised, designed and their cytotoxicity were tested against cancer cell lines. The study concludes that ferrocene-indole with indole substituted at position 2 and 7 are more active in cytotoxicity compared to the others in the series. The employed synthesis method was a resemblance of Steglich Esterification, with EDC·HCl acted as coupling agent and DMAP as catalyst. A precursor molecule, ferrocenephenylenediamine was synthesised through EDC coupling. In addition, a series of ferrocenephenyldiamide-indole was synthesised using the mentioned precursor, with all six possible indoles substituted by the precursor. Characterisation of the compounds were accomplished by Nuclear Magnetic Resonance (NMR), Fourier-Transform Infrared Spectroscopy (FT-IR), CHN Elemental Analysis and Mass Spectroscopy (MS). Meanwhile, MTS Assay was chosen as a biological evaluation of the six ferrocene-indole hybrids. 2020-01-01T00:00:00Z